What is involved

REACT-GE and GenOMICC COVID-19 studies

To take part in the REACT-GE and GenOMICC COVID-19 studies, you will need to have been invited to do so. If you have received an invitation, you will have a REACT ID that you will need to sign up.


What happens when I join the study?

Once you have registered to take part, you will be contacted by phone, text message or email by Trust MSS, our sample collection partner, to arrange an appointment at the test centre most convenient to you, which will be detailed on your invitation.

Your information will only be used by them to schedule your appointment.

Prior to your appointment you will be asked to answer an online questionnaire about you and your health and lifestyle. This will take approximately 15-20 minutes to complete. If you cannot access the questionnaire online, then this can be done by telephone by calling 0808 2819 535.

At your appointment, you will need to bring ID such as a driver licence or a bank card, to confirm your identity. You will need to sign a consent form (GenOMICC Study and REACT-GE Study) that grants us permission to include you in the studies and to take your blood and urine samples and physical measurements. If you agree, the nurse will then take up to 45ml, or approximately three tablespoons, of blood. The samples will be taken from a single needle into five different tubes in total.

We will also measure your height, weight, waist circumference, grip strength, lung function and blood pressure, and we will ask you to provide a urine sample. Your lung function will be measured by means of a spirometer and/or a simple exercise test while measuring your blood oxygen level with a pulse oximeter. Your appointment should take around 40 minutes.

After your appointment you may be invited to take part in a survey about your recent food intake.

One of your blood samples will be sent to a laboratory run by GenOMICC at the University of Edinburgh, to prepare it for genomic sequencing by Illumina, our partners at Cambridge University. The remaining samples will be sent to a laboratory in London operated by Affinity Biomarkers who will process them and prepare them for sending to other academic and commercial partners in the UK and overseas to carry out analyses for research purposes.

We will also need your consent to sequence your DNA and store it, and to access and store relevant parts of your health records, now and in the future.

Please download and read the Participant Information Sheets below for more details on the studies and what it means to consent to be part of them.

GenOMICC COVID-19 Study Participant Information Sheet

REACT-GE Study Participant Information Sheet

You can read our privacy notices here.


You can find the directions to the sample collection centres by clicking the links below (PDFs):

Further information for other centres will be added as they're available.

Why have I been invited to take part?

You have been invited to take part in this study because you previously took part in a REACT study carried out by Imperial College London and tested positive for either COVID-19 infection (via an at-home swab test) or past COVID-19 infection (via an at-home antibody test). You also kindly agreed that we could invite you to take part in further research studies.

Why do you need my health records and how do you keep them safe?

We need your health records because a DNA sequence does not have much meaning without them. They allow us to ‘interpret’ it properly. For instance, childhood infections could be important. And because it is becoming clear that COVID-19 has long lasting consequences, we need to know what happens to you next healthwise. This information could help predict which people might be at risk of late onset complications. Your genome could provide vital help here.

We make sure that your sequence and health data are confidential and secure.

Privacy and confidentiality

Participant privacy and confidentiality is key to our studies. To maintain your privacy, any information that could identify you is removed from your health records and your health data before we get it. This process is called de-identifying.

Keeping your data secure

Nobody but approved health researchers – from academia, industry and the NHS will be able to use the de-identified genomic and health data in our data centre to discover more about COVID-19 There are more details of all the processes we have put in place to ensure your data is safe here.

After your genome has been sequenced and mapped, it is stored in The National Genomic Research Library which is a secure national resource of genomic, health data and samples. Genomics England is its guardian.

Take part in the research

If you have received a letter inviting you to join the REACT-GE and GenOMICC COVID-19 studies, then please complete the form so we can set you up.

  • You have your REACT ID as detailed in your invitation
  • We have the right details for you
Please make sure:
Sign up now