About us

REACT-GE and GenOMICC COVID-19 studies

The REACT programme

The REACT programme, which stands for Real-time Assessment of Community Transmission, is a series of studies that seeks to improve understanding of how the COVID-19 pandemic is progressing across England. Led by doctors and researchers at Imperial College London, REACT is being carried out in partnership with Imperial College Healthcare NHS Trust and Ipsos MORI.

Doctors and researchers from Imperial College London are working with the GenOMICC research team, who are conducting a COVID study with similar groups of people, to help everyone speed up the process of sample collection, analysis and ultimately improve our understanding of the virus.

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GenOMICC

GenOMICC is a global community of doctors and scientists who are working together to treat serious illnesses and find out why people end up needing intensive care. Together, they use blood samples to sequence and analyse DNA for the NHS.

Genomics England

Genomics England is the guardian of the National Genomics Research Library, where data collected from this study will be kept. This library contains the health data and genetic sequences of tens of thousands of people, including from the 100,000 Genomes Project. The data is made available to approved researchers to make discoveries and help develop new treatments and medicine. Find out more about the NGRL on Genomics England's website.

About the studies

The GenOMICC COVID-19 Study aims to find out whether people’s genes have an impact on how badly they get COVID-19 and why some people become seriously ill with the virus while others are hardly affected.

The REACT-GE Study focuses on identifying links between the proteins and small molecules present in your blood, urine and your DNA and how your genetic code is expressed in your body in relation to the susceptibility and severity of COVID-19.

Our trained nurses and phlebotomists were provided through Trust MSS. They collected consent and participants' samples and measurements at the appointment.

For both studies we will carry out an in-depth analysis of the samples donated by people who have tested positive for COVID-19 infection or antibodies and have suffered symptoms which did not require hospitalisation or even showed no symptoms at all.

Together, we aim to support the development of better treatments or vaccines for COVID-19. The REACT-GE Study has now ended, as we focus on understanding the longer term symptoms and health impacts of 'long COVID'. If you might be interested in taking part in the study on long COVID, then you can find out more and register your interest here. You do not need to have suffered from long COVID, but must have had a positive test for COVID-19, to take part.


What is a genome and why is it important?

The genome is the body’s instruction manual and contains all the information needed to make you, run you and repair you. You have a copy in almost all the 37 trillion cells in your body. It’s unique to you and you inherit it from your parents. It’s made of DNA and is written in DNA’s special code. Each one of the 3 billion letters in a genome can be read using a technique called sequencing.

Find out more by watching our short film below.